Estrolief contains key components and vitamins to aid in hormone metabolism.

DIM is the bioactive metabolite of Indole-3-Carbinol (I3C) from cruciferous vegetables. DIM has been shown in studies to better aid in the estrogen metabolism than I3C due to its actions further down the pathway. DIM enhances the estrone conversion to 2-OH-estrone (protective) and decreases the conversion to 4-OH & 16-OH metabolites (persistently estrogenic).

SDG (Secoisolariciresinol diglucoside) has a strong affinity to the receptor of 4-, 16-OH estrone. It exerts an "amphoteric effect" to reduce the harmful estrogenic effect of 4-OH & 16-OH estrones by occupying the receptors while alleviating menopausal symptoms.

D-glucarate has been shown to inhibit beta-glucuronidase- an enzyme that recycles toxins and hormone metabolites back into the blood stream rather than excreted and, thus, slows down the detoxification process.

Formulated with essential coenzymes: 5-MTHF, pyridoxine-5-phosphate, and B12 to support steroid hormone detoxification (ie. methylation, transamination).

Gluten-Free / Vegan / Non-GMO

Suggested Use / Directions:
Adults – Take 2 capsules per day, or as directed by a healthcare practioner.

Serving Size:
2 capsules

Amount Per Serving:

Vitamin B6 (from pyridoxine HCL & pyridoxal-5’-phosphate) ... 70 mg
Folate (from calcium L-5-MTHF) ... 700 mcg
Vitamin B12 (methylcobalamin) ... 500 mcg
3,3’-Diindolylmethane (DIM) ... 108 mg
Calcium d-glucarate ... 430 mg
Flax Extract (Linum usitatissimum) (seed) (20% Secoisolariciresinol diglucoside) ... 200 mg

Other Ingredients:
Silicon dioxide, L-leucine, hypromellose (capsule)


Do not use if you are pregnant. Consult a healthcare practioner prior to use if you are atempting to conceive; if breastieeding; or if you are taking any medications.