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Insulin Resistance

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OmegaGenics® EPA-DHA 2400 Fish Oil - Lemon (150 Milliliters)

OmegaGenics® EPA-DHA 2400 Fish Oil - Lemon

Metagenics

Size:150 Milliliters
$67.99

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Dosage instructions

  • Dosage amount:

    1.00 Teaspoon (tsp)

  • once per day

Size:
$32.99

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Dosage instructions

  • Dosage amount:

    1.00 Capsule

  • twice per day

Size:
$27.99

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Dosage instructions

  • Dosage amount:

    1.00 Capsule

  • once per day

  • Additional notes

    "in divided doses, with meals."

Size:60 Softgels
$29.99

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Dosage instructions

  • Dosage amount:

    1.00 Softgel

  • once per day

Size:120 capsules
$41.99

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Dosage instructions

  • Dosage amount:

    1.00 Capsule

  • once per day

Size:
$67.99

Sign up for exclusive store pricing

Dosage instructions

  • Dosage amount:

    1.00 Capsule

  • once per day

  • Additional notes

    "in divided doses, with meals"

Size:
$57.99

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Dosage instructions

  • Dosage amount:

    1.00 Capsule

  • twice per day

Size:60 tablets
$21.99

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Dosage instructions

  • Dosage amount:

    1.00 Tablet

  • twice per day

Size:
$59.99

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Dosage instructions

  • Dosage amount:

    2.00 Capsules

  • once per day

Lifestyle recommendations

Nutrition
  • Nutrition: insulin-centric, not dogmatic

    I differentiate between:

    • “Overfueled, under-muscled, inflamed” (most IR) vs
    • “Lean, high stress, dysregulated cortisol, maybe reactive hypoglycemia” (different handling of carbs)

    Baseline nutrition principles (for 90% of IR cases)

    Macro structure per meal:

    • Protein: 1.6–2.0 g/kg ideal body weight per day; 25–40 g per meal
    • Carbs: front-loaded earlier in the day; 15–30 g net per meal to start for most; mostly from whole-food sources
    • Fat: fill the remainder with mono- and saturated fats from whole foods, avoid industrial seed oils

    Food rules that move the needle:

    1. No naked carbs.
      Always pair carbs with protein + fiber + fat.
    2. Early time-restricted eating (if adrenals tolerate it):
      • 10–12 hr eating window to start
      • Prefer 8 am–6 pm over skipping breakfast and eating late
    3. Prioritize protein at breakfast:
      • 30–40 g protein, minimal sugar, modest carbs
      • Example: 3 eggs + 100 g smoked salmon + sautéed greens in olive oil
    4. Carb sourcing and cutoffs:
      • Prefer: root veg, whole fruit (2 servings/day), lentils/beans (if tolerated), quinoa, buckwheat, well-cooked oats (if non-celiac)
      • Reduce drastically: liquid sugar, fruit juice, sweetened coffee/tea, refined grains, most ultra-processed snacks
      • For moderate-to-high IR or NAFLD: start around 50–80 g net carbs/day for 4–8 weeks, then increase based on response
    5. Fats:
      • Include: extra virgin olive oil, avocado, pasture-raised eggs, grass-fed meats, fatty fish, nuts/seeds (watch portions), full-fat fermented dairy (if tolerated)
      • Minimize: soybean, corn, canola, cottonseed, “vegetable oil” blends, repeated deep-frying
    6. Fiber & polyphenols:
      • Aim: ≥30–40 g/day fiber
      • Ground flax/chia, psyllium, lots of non-starchy veg, berries
      • Polyphenol-rich: green tea, coffee (without sugar), cocoa, berries, olives, herbs/spices (cinnamon, turmeric, rosemary, oregano)

    Example day (for a typical overweight IR client):

    • Breakfast:
      • Omelet with 3 eggs, spinach, mushrooms, feta in olive oil
      • ½ avocado
      • Green tea or black coffee
    • Lunch:
      • 150–200 g grilled chicken or salmon
      • Large mixed salad (olive oil + vinegar), olives
      • ½–1 cup cooked lentils or chickpeas (depending on carb tolerance)
    • Snack (usually optional):
      • 20–30 g nuts or a protein shake with unsweetened almond milk + fiber
    • Dinner:
      • 150–200 g meat/fish
      • 1–2 cups non-starchy veg with butter/ghee/olive oil
      • Small serving (½–1 cup) starchy veg (sweet potato, winter squash) depending on glucose response

    For lean, stressed, “wired-tired” IR or reactive hypoglycemia

    • Don’t be too aggressive with carb restriction initially
    • Use balanced meals with 25–30 g protein + 20–30 g low-glycemic carbs + 10–20 g fat
    • Avoid long fasting windows early; prioritize circadian rhythm first, then consider gentle compression of eating window.
Movement
  • Movement & body composition

    Insulin resistance is fundamentally a muscle and liver issue.

    Non-negotiables:

    1. Resistance training:
      • 3x/week, 30–45 minutes
      • Focus on big patterns: squat, hinge (deadlift/hip thrust), push, pull, loaded carry
      • Goal: progressive overload; even bodyweight + bands will work at first
    2. Postprandial walking:
      • 10–15 min walk after main meals (especially largest carb load)
      • This alone can drop postprandial glucose 20–30 points in many people
    3. Daily movement target:
      • 7,000–10,000 steps/day as a minimum effective dose
    4. For advanced / plateaus:
      • 1–2 sessions/week of higher-intensity intervals (e.g., 6–10 × 30–60 sec fast with full recovery).
      • Use cautiously in those with high cortisol/overtraining.
Sleep
  • Sleep & circadian rhythm

    One bad night of sleep can create temporary insulin resistance.

    Core practices:

    • 7.5–9 hours in bed, consistent wake time
    • Morning light exposure within 30–60 min of waking, 10–20 min outside
    • Block blue light 2–3 hours before bed (or use warm/red lighting)
    • Cool, dark, quiet bedroom
    • No late heavy meals; finish dinner at least 3 hours before bed

    If sleep apnea is suspected (snoring, daytime sleepiness, large neck, refractory IR), push for assessment—treating apnea is a massive IR lever.

Stress Management
  • Stress & autonomic balance

    Chronic sympathetic overdrive worsens hepatic gluconeogenesis and IR.

    Minimal effective interventions:

    • 10–20 minutes/day of parasympathetic work:
      • Slow breathing (e.g., 4–6 breaths/min)
      • Yoga nidra, meditation, tai chi, qigong
      • Even a daily nature walk without phone
    • Track subjective “stress load” and correlate with CGM/ SMBG if using it.

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