Hormone Health Support (As Needed)

1 Capsule

once per day

Ongoing

Additional notes

"DIM — diindolylmethane — is a compound derived from cruciferous vegetables that your body produces when it digests broccoli, cauliflower, and Brussels sprouts. The problem is that the amount you would need to eat to achieve a therapeutic effect is not realistic as a daily practice. More importantly, standard DIM supplements have poor bioavailability — the compound is fat-soluble and poorly absorbed in most capsule forms. DIM-Evail uses the BioResponse microencapsulation technology that makes DIM three times more bioavailable than standard formulations, delivering a consistent therapeutic dose that reaches the tissues where it matters. In hormonal terms, DIM promotes estrogen metabolism through the 2-hydroxy pathway — the pathway associated with bone protection and reduced inflammatory signaling — and away from the 4-hydroxy and 16-hydroxy pathways that are associated with increased cancer risk and inflammatory estrogen metabolites. For women on BHRT, it ensures the estrogen being supplemented is being metabolized safely and efficiently. For women not on hormones, it supports the most protective use of the estrogen the body is still producing. Either way, the metabolism of estrogen matters as much as the level."

2 Capsules

once per day

Ongoing

Additional notes

"Calcium D-Glucarate After estrogen is metabolized by the liver, it is conjugated — chemically packaged — for excretion through the bile and out through the gut. Under normal circumstances, that conjugated estrogen leaves the body. The problem is a gut enzyme called beta-glucuronidase, produced by dysbiotic bacteria, that deconjugates estrogen in the intestine — essentially unwrapping the package and allowing the estrogen to be reabsorbed rather than excreted. The result is recirculation of estrogen that should have been cleared, which disrupts the estrogen balance that bone remodeling depends on and increases the load on the liver's detoxification pathways. Calcium D-Glucarate inhibits beta-glucuronidase directly, supporting proper estrogen clearance through the gut and reducing the recirculation burden on the entire hormonal system. It works upstream — in the gut, before recirculation happens — making it one of the most logical complements to DIM in any hormone support protocol. Together they address both sides of estrogen metabolism: the pathway it takes through the liver and the clearance route through the gut."

1.00 Capsule

once per day

Ongoing

Additional notes

"with meals in divided doses.-Methylation is one of the most fundamental biochemical processes in the body — and one of the most commonly impaired. It is required for estrogen detoxification, DNA repair, neurotransmitter synthesis, and the formation of the collagen matrix that gives bone its structural integrity. The MTHFR gene variant, which impairs the enzyme that converts folate into its active methylated form, is present in a significant portion of the population and is particularly common in women with bone loss, early menopause, and cardiovascular risk. People with this variant cannot effectively utilize the synthetic folic acid found in most B-complex supplements — they require methylfolate and methylcobalamin, the forms the body can use directly without conversion. Methyl-Guard Plus delivers the full methylation support stack in active forms: methylfolate, methylcobalamin, pyridoxal-5-phosphate, and riboflavin-5-phosphate. Beyond estrogen metabolism, adequate methylation is required to regulate homocysteine — an amino acid that, when elevated, directly interferes with collagen crosslinking in bone matrix and is an independent risk factor for osteoporotic fracture even in people with normal bone density. This is foundational chemistry. Everything downstream depends on it working."

1.00 Capsule

twice per day

Ongoing

Additional notes

"between meals- Gelatinized Maca Root Maca is one of the few botanicals with direct clinical evidence for its effects on postmenopausal bone health — not through phytoestrogenic activity, which makes it appropriate for women with estrogen-sensitive conditions and for BRCA carriers, but through its effects on the hypothalamic-pituitary axis, the upstream hormonal control system that governs the production and signaling of sex hormones, adrenal hormones, and the feedback loops that regulate bone remodeling. Multiple studies in postmenopausal women have shown that maca supplementation reduces bone resorption markers and supports hormonal balance through this pituitary-level mechanism rather than by directly mimicking estrogen. The gelatinized form is the critical distinction — raw maca contains starch compounds that impair absorption and can cause digestive discomfort, while gelatinization removes those compounds and concentrates the active alkaloids responsible for the hormonal effects. For women who cannot or choose not to take hormone replacement therapy, maca represents one of the most clinically supported non-hormonal options for maintaining the hormonal environment that bone health depends on."

1 Capsule

once per day

Ongoing

Additional notes

"with meal.- Micronized DHEA DHEA is the most abundant steroid hormone in the human body at its peak — and one of the most rapidly declining. Production begins falling in the mid-20s and continues declining at roughly 2% per year, reaching levels in the 60s and 70s that are a fraction of what they were at 25. DHEA is the precursor from which both estrogen and testosterone are synthesized in peripheral tissues including bone tissue itself — meaning that adequate DHEA is a prerequisite for local sex hormone production in the skeleton independent of what the ovaries or adrenal glands are producing centrally. Multiple clinical studies have linked DHEA supplementation in postmenopausal women with improved bone mineral density, improved bone turnover markers, and better musculoskeletal outcomes. Micronized DHEA is the form with the most complete absorption — standard DHEA has inconsistent bioavailability, while micronization produces particle sizes that absorb reliably across the intestinal mucosa. This product requires physician oversight and a baseline DHEA-S blood test before starting — the goal is restoration to a youthful physiological range, not supplementation beyond it. It is included in this collection because the evidence for its role in bone health is direct, the population most likely to benefit is precisely the postmenopausal women we work with, and the gap between how commonly it is deficient and how rarely it is tested represents one of the most addressable blind spots in conventional bone health care."