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Folate 5000 Plus

Pure Encapsulations

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Folate 5000 Plus product image
SKU: PUR-FLP56

Activated folate, vitamin B12 and B6 combination*

  • 5, 000 mcg of activated folate per capsule
  • Combination of activated B vitamins
  • Made with hypoallergenic, vegan ingredients

Activated folate, vitamin B12 and B6 combination*
Folate 5, 000 Plus provides 5, 000 mcg of folate as 5-methyltetrahydrofolate (5-MTHF), the universally metabolized and biologically active form of folate, combined with activated vitamins B12 and B6. Optimal levels of these B vitamins have been associated with cellular, cardiovascular, neurological and psychological health. Activated B vitamins provide methyl groups to support healthy methylation, a key regulator of genetic expression and cellular function. Healthy methylation is vital for cellular health, hormone and neurotransmitter production, and energy metabolism. Research suggests that B vitamins help maintain healthy nervous system function. In a randomized controlled study, a combination of methylfolate, methycobalamin and pyridoxal-5-phosphate promoted healthy epidermal nerve fiber density and nerve comfort. These vitamins also enhance healthy endothelial function and play a vital role in the metabolism of homocysteine.


Take 1 capsule daily, with a meal, or as directed by a health professional.


Serving Size: 1 vegetarian Capsule

Amount Per Serving
Folate ... 8,333 mcg DFE (L-5-MTHF 5,000 mcg)
(as Quatrefolic® (6S)-5-Methyltetrahydrofolic acid, glucosamine salt)
Vitamin B12 ... 1, 000mcg
(as methylcobalamin)
Vitamin B6 ... 25mg
(as pyridoxal 5’ phosphate (activated B6))

Other Ingredients: hypoallergenic plant fiber (cellulose), vegetarian capsule (cellulose, water)

Quatrefolic® is a registered trademark of Gnosis S.p.A. Patent No. 7, 947, 662


If pregnant or lactating, consult your physician before taking this product. At this time, there are no known side effects or precautions. Consult your physician for more information.

Folate may adversely interact with chemotherapeutic drugs. Consult your physician for more information.


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